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2026-10-22 05:39:43 -

Bridging Proteomics and Genomics: The Engineering and Application of Antibody-Oligonucleotide Conjugates

Antibody-oligonucleotide conjugates (AOCs) represent a rapidly expanding class of chimeric molecules that merge the precise target recognition of monoclonal antibodies with the functional, structural, or amplifiable properties of nucleic acids. By combining these two distinct biological macromolecules, researchers are unlocking unprecedented capabilities in both targeted therapeutics—such...

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